wang jiewen created a new article
2 yrs

We want to kill tumor cells, but we don’t want to harm the nontumor cells, and at the moment, that’s still a challenge. | #succinimide

We want to kill tumor cells, but we don’t want to harm the nontumor cells, and at the moment, that’s still a challenge.

We want to kill tumor cells, but we don’t want to harm the nontumor cells, and at the moment, that’s still a challenge.

Tweaking the sites where the linker and the payload attach to the antibody has been an area where many ADC makers are working. Except for Enhertu, all the FDA-approved ADCs are heterogeneous: the number of linker-payload groups attached to each antibody varies. Creating homogeneous ADCs, i